Lebrikizumab for nasal polyps and sinusitis
Part of Immune system & allergy, Lungs & breathing clinical trials.
This trial tests a new injectable medicine (lebrikizumab) for people with chronic sinusitis and nasal polyps that steroid treatments haven't controlled. It aims to reduce polyp size and improve breathing, smell, and congestion.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with chronic sinusitis and have nasal polyps on both sides, confirmed by a doctor with a scope.
- You have moderate to severe nasal congestion (score 2 or 3 out of 3) and at least one other symptom like loss of smell or runny nose.
- You have taken steroid pills or had sinus surgery for polyps in the last 2 years, or you cannot take steroids for medical reasons.
- Your nasal polyps must be at least a 5 on an 8-point severity scale (doctor will check).
- If you have asthma, it must be stable for 3 months on your regular medication.
- You have not had any sinus surgery in the last 6 months, and no certain treatments like other biologics or immunosuppressants recently.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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