Cerebrolysin after late clot removal for stroke
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether Cerebrolysin (a medication given through an IV) can help improve recovery after a stroke when given after a successful clot-removal procedure that happened several hours after the stroke began. It is being tested in people who had a large-vessel stroke in the front of the brain and meets certain imaging criteria. The goal is to see if the drug can reduce disability and improve recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old
- You had a stroke caused by a blocked artery in the front of the brain, and the clot was removed with a procedure that started more than 6 hours but within 24 hours after symptoms began
- Before the stroke, you were fairly independent in daily activities (able to do things like walking and self-care without major help)
- The clot removal procedure successfully reopened the blocked artery (confirmed by the doctor after the procedure)
- Scans after the stroke showed there was still a good amount of brain tissue that could be saved, and you have moderate to good collateral circulation (extra blood flow)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This trial tests whether giving a clot-dissolving medication directly into the brain's blood vessels during a standard procedure (mechanical thrombectomy) can improve outcomes for people with a stroke caused by a blockage in a medium-sized artery. It may be an option for patients who arrive at the hospital within 24 hours of symptom onset and have enough salvageable brain tissue.
This trial tests if removing a large blood clot from the brain up to 3 days after a stroke improves recovery compared to standard medical care alone. It is for patients who have a severe stroke and are otherwise healthy enough for the procedure.
This study tests whether a clot-busting drug called pro-urokinase can help people with a stroke in the back of the brain when given later than usual (4.5 to 9 hours after symptoms start). The goal is to see if it improves recovery and reduces disability.
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