Methadone by mouth for knee or hip surgery recovery
Part of Bones, joints & muscles, Pain clinical trials.
This study tests whether taking methadone pills after knee or hip surgery can help manage pain better than usual care. It may offer an alternative for people who cannot have nerve blocks.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are having elective arthroscopic surgery on your knee or hip.
- You are at least 18 years old.
- You are not pregnant or breastfeeding.
- You do not have a history of breathing problems (respiratory compromise).
- You are not allergic to opioids.
- You have not received a nerve block before surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether giving a single dose of methadone during surgery can improve pain relief after the operation, possibly reducing the need for other painkillers and helping you recover more comfortably. It is for people having certain planned surgeries that require an overnight stay in the hospital.
This study tests whether a single dose of methadone given during hip replacement surgery can better control pain and reduce the need for other opioid painkillers afterward. It may help you recover with less pain and fewer side effects.
This Phase 3 trial tests whether giving methadone during hip or knee replacement surgery can reduce pain after surgery. It may help some people use less rescue pain medicine afterward, but it also has safety checks for kidney, liver, heart, and opioid-related risks.
This trial tests if adding methadone during knee replacement surgery can better control pain after the operation and reduce the need for opioid painkillers. It may help you recover with less discomfort and fewer side effects from strong pain medicines.
This study tests whether methadone, a type of pain medicine, helps control pain better after knee replacement surgery. It is for people who have not used narcotics recently and are otherwise healthy.
This trial tests if methadone given through a vein can control pain better after heart surgery done through a breastbone incision. It may be an option for adults having planned heart surgery who are expected to wake up and breathe on their own within 12 hours.
Hear when a new Arthroscopic Knee Repair trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.