Psilocybin for chronic back pain and depression
Treatments studied
Part of Bones, joints & muscles, Mental health, Pain clinical trials.
This trial tests if psilocybin, a psychedelic drug, can help people with long-term low back pain who also have depression. If you qualify, you'll receive psilocybin in a controlled setting, and researchers will see how it affects your pain and mood.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 21 and 80 years old.
- You have had low back pain for at least 3 months, and it has bothered you on most days for the past 6 months.
- You have at least moderate depression symptoms (score of 17 or more on a depression rating scale).
- You can speak and read English fluently and have a high school diploma or equivalent.
- You are willing to avoid certain medications, supplements, and recreational drugs around the study sessions.
- You have not used psychedelic drugs more than 10 times in your life and none in the past 5 years.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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