Stress hormone system study after heart surgery
Treatments studied
Part of Heart & circulation clinical trials.
This study looks at how your body's stress hormone system (the HPA axis) works after heart surgery if you develop vasoplegic syndrome (a serious drop in blood pressure). The goal is to understand if giving extra steroids might help. If you are scheduled for heart surgery with a heart-lung machine, you may be able to join.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older.
- You are scheduled for heart surgery that uses a heart-lung machine (called extracorporeal circulation).
- You have not taken certain medicines (like steroids, some antifungals, seizure drugs, diabetes pills, antidepressants, or antipsychotics) in the last 3 months.
- You do not have a known problem with your adrenal glands or pituitary gland.
- You have not had a heart transplant.
- You are not on a mechanical heart/lung support device after surgery and are not in legal custody.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at blood flow in small and large vessels during heart surgery to understand and predict vasoplegic syndrome, a dangerous drop in blood pressure. It may help find patients at risk and improve their care.
This trial tests whether adding two common medicines, hydrocortisone and fludrocortisone, to standard care can help people who are at higher risk during planned heart surgery. It aims to see if this combination can reduce serious complications after surgery.
This Phase 3 trial tests whether hydrocortisone plus vasopressin (or related hormone treatments) can improve shock in adults after a resuscitated cardiac arrest. It targets people who remain very low in blood pressure despite fluids and need strong IV medicines to maintain blood pressure.
This study looks at how a blood-pressure hormone system (RAAS) changes during coronary artery bypass surgery. It may help researchers understand better how to manage blood pressure and heart stress around the time of surgery.
This study looks at how changes in blood pressure during heart surgery affect recovery. If you are having scheduled heart surgery with a heart-lung machine, you may be able to join.
This study looks at how blood pressure medications affect low blood pressure episodes that happen during and after heart surgery. Researchers want to understand if the number of blood pressure drugs you take before surgery changes how your body handles blood pressure during the operation.
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