Personalized ventilation for ARDS patients on breathing machines
Part of Lungs & breathing clinical trials.
This trial tests a personalized ventilation method that adjusts how the breathing machine delivers air based on your lung's air and blood flow match. It aims to improve breathing for people with moderate to severe ARDS who are already on a ventilator and will be placed on their stomach.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 84 years old.
- You have moderate to severe acute respiratory distress syndrome (ARDS).
- You are on a breathing machine (invasive mechanical ventilation).
- Your doctor plans to have you lie on your stomach (prone position).
- You do not have any of the excluded conditions like pregnancy, severe blood pressure instability, brain pressure issues, lung air leaks, pacemaker, chest burns, very high sodium, or current participation in another trial.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests whether using a special imaging technique (electrical impedance tomography) to set the breathing machine's pressure can improve oxygen levels and lung function in patients with moderate to severe ARDS, a serious lung condition.
This trial tests a special monitoring technique called EIT (electrical impedance tomography) to help doctors set the best breathing machine pressure for people with ARDS. It may help improve oxygen levels and protect the lungs.
This trial tests a more tailored way to set the amount of air delivered by a ventilator in people with severe ARDS. The goal is to see if personalized breathing settings can improve breathing and heart-related monitoring while patients are in intensive care.
This trial studies two ways to measure how much of your lungs can open up again (recruitability) to help doctors set the best breathing machine pressure. It may help improve oxygen levels in patients with severe lung injury.
This study tests a method called EIT-guided PEEP titration to find the best ventilator pressure setting for people with moderate to severe ARDS who are also placed face down (prone) to improve breathing. The goal is to see if this helps your lungs recover better.
This study tests whether a customized breathing machine approach ("precision ventilation") is better than usual care for patients with ARDS. The goal is to improve oxygen levels and recovery while avoiding lung damage.
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