Clinical trials
Respiratory Distress Syndrome clinical trials
Below are recruiting respiratory distress syndrome clinical trials, each written for real people, not researchers. We’re tracking 200 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07463885Recruiting
Breathing on your own vs machine breathing for low oxygen
This study tests whether letting patients with serious breathing problems breathe on their own (with a breathing tube still in place) is better than the usual way of using the ventilator to do all the breathing. It may lead to faster recovery and less harm.
Oslo, OsloAges 18 years+ - NCT06776783RecruitingPhase 3
Testing a new surfactant for breathing problems in premature babies
This study tests a new medicine called APC-0101, a type of surfactant, for premature babies with breathing problems (respiratory distress syndrome). It may help their lungs work better and reduce the need for more breathing support.
Little Rock, ArkansasAges 1 hour–1 day - NCT05857891Recruiting
Erythropoietin to help clear lung fluid in ARDS
This trial tests whether erythropoietin (EPO), a medicine that affects red blood cell production, can help clear extra fluid from the lungs in people with acute respiratory distress syndrome (ARDS). If it works, it could improve breathing and reduce lung fluid buildup during critical illness.
Wenzhou, ZhejiangAges 18 years+ - NCT06013319RecruitingPhase 3
Esmolol for better oxygen in ARDS patients
This trial tests if esmolol, a heart-slowing drug, can improve oxygen levels in patients with acute respiratory distress syndrome (ARDS) who are on a breathing machine. It may help by adjusting heart rate to a specific range.
Jinan, ShandongAges 18–65 - NCT04158479Recruiting
Registry for people on ECMO life support
This registry collects information about people who are placed on ECMO, a heart-lung machine used to support breathing and/or circulation. It may help doctors better understand who benefits and how to manage ECMO in the future.
Beijing, Beijing MunicipalityAges Any age - NCT05562505Recruiting
Using ECMO to help you breathe, sit up, and come off a ventilator
This trial tests whether a heart-lung machine called venovenous ECMO can help people with severe breathing failure get less sedated, get extubated (have the breathing tube removed), and start moving. It’s for certain adults who are on a ventilator for a short time and have specific oxygenation problems.
Darlinghurst, New South WalesAges 18–65 - NCT05844579Recruiting
Early breathing and mobilization support for ICU lung injury
This study looks at whether starting early movement and breathing-related care while in the ICU helps people with ARDS (a serious lung condition). You may be eligible if you recently needed a breathing machine and are expected to need it for a bit longer.
TokyoAges 16 years+ - NCT07750288Recruiting
Studying shortness of breath in children with acute respiratory distress
This study looks at how shortness of breath (dyspnea) relates to the progression of pediatric acute respiratory distress syndrome (PARDS), a severe lung condition in children. It aims to understand breathing difficulties better to improve care.
SantiagoAges 1 month–18 years - NCT07711964RecruitingPhase 4
Finding the best steroid dose for ARDS patients on a ventilator
This trial tests different doses of corticosteroids to find the best one for people with acute respiratory distress syndrome (ARDS) who are on a breathing machine. It aims to improve recovery while reducing side effects.
TaipeiAges 18 years+ - NCT06642285Recruiting
Preventing nasal injuries in preterm babies on breathing support
This study tests if using special care steps can prevent nose sores in preterm babies who need breathing support through a mask or nasal prongs. It may help protect your baby's delicate nose from injury.
Kafr ash Shaykh, Kafr el-Sheikh GovernorateAges 7 months–9 months - NCT07686315Recruiting
Safer breathing with advanced monitoring on a ventilator
This trial is testing a new way to monitor your breathing while you are on a ventilator, to make it safer. It is for people who need a ventilator for reasons other than lung failure, like after a coma, injury, or severe infection.
Milan, LombardyAges 18 years+ - NCT07673250Enrolling by invitation
Personalized breathing settings for ECMO patients
This study tests whether personalized breathing machine settings can improve outcomes for people on ECMO (a heart-lung support machine). It is designed for patients who have had or are waiting for a lung or heart transplant.
La Jolla, CaliforniaAges 18 years+ - NCT07674953Recruiting
CPAP and oxygen delivery in preterm infants
This study looks at how different levels of CPAP (a breathing machine that helps keep the lungs open) affect oxygen delivery and lung expansion in preterm babies. It may help doctors understand the best settings for infants who need breathing support.
Little Rock, ArkansasAges Any age - NCT06690801Recruiting
Nitric oxide breathing gas for children with lung failure
This trial tests whether adding a breathing gas called nitric oxide to standard care helps children with severe lung failure (ARDS) recover faster. It is for children on a breathing machine who still have low oxygen levels.
Los Angeles, CaliforniaAges birth–21 years - NCT07603310Recruiting
PEEP levels in ARDS based on lung response
This study tests whether adjusting ventilator settings based on how well your lungs respond can improve oxygen and reduce damage in patients with moderate to severe ARDS, within the first 36 hours of diagnosis.
Rancagua, Región del Libertador General Bernardo O’HigginsAges 18 years+ - NCT06650137Recruiting
Using Diaphragm Ultrasound to Find the Cause of Breathing Trouble
This study tests if ultrasound of your diaphragm (the muscle that helps you breathe) can help doctors find the cause of sudden breathing trouble. It may help patients who come to the emergency room with fast or difficult breathing and low oxygen levels.
Nîmes, GardAges 18 years+ - NCT07576660RecruitingPhase 3
Dexamethasone for lung injury from sepsis
This trial tests whether the steroid dexamethasone can help people with sepsis who develop acute respiratory distress syndrome (ARDS), a severe lung injury. If you have an infection and need breathing support, this study may help find a better treatment.
Nanjing, JiangsuAges Any age - NCT07558265Recruiting
Comparing breathing support methods in the emergency department
This study tests two common ways to help people who are having trouble breathing in the emergency room: a face mask that pushes air into the lungs (non-invasive positive pressure ventilation) or high-flow oxygen through small tubes in the nose (high-flow nasal oxygen). The goal is to find which method works better to avoid needing a breathing tube.
Tucson, ArizonaAges 18 years+ - NCT07558538RecruitingEarly Phase 1
Inhaled Growth Factor Treatment for Severe Lung Failure
This early-stage trial tests whether an inhaled medication called recombinant human keratinocyte growth factor-2 (rh-KGF-2) can help patients with acute respiratory distress syndrome (ARDS)—a serious condition where the lungs cannot deliver enough oxygen to the blood. The drug is designed to help repair lung tissue damage.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07550218Recruiting
Surfactant Delivery Methods for Premature Babies with Breathing Problems
This study looks at different ways doctors give a life-saving medication called surfactant to premature babies who are struggling to breathe. Researchers want to understand which delivery methods work best and help improve care.
GothenburgAges Any age - NCT07542366Recruiting
Testing a new lung imaging method in ICU patients
This study tests whether a special imaging technique called EIT (electrical impedance tomography) combined with a safe contrast injection can measure blood flow in the lungs of patients on breathing machines. If it works, it could help doctors better manage critically ill patients.
Wuhu, AnhuiAges 18 years+ - NCT06694311Recruiting
Testing CPAP and high-flow oxygen for ARDS
This study tests two types of breathing support—CPAP (a mask that pushes air into your lungs) and high-flow nasal oxygen (a special tube in your nose)—to see which works better for people with ARDS, a serious lung condition. It may help you breathe more easily without needing a breathing tube.
Barcelona, BarcelonaAges 18–80 - NCT07450846Recruiting
Heart-lung interaction in severe breathing problems
This study looks at how the heart and lungs interact in patients with acute respiratory distress syndrome (a severe lung condition) who are on a breathing machine. Researchers will use ultrasound to check heart function at different times during treatment.
Le Kremlin-BicêtreAges 18 years+ - NCT07442669Recruiting
Lung ultrasound for surfactant decision in premature babies
This trial uses a lung ultrasound score, a type of ultrasound, to decide when to give surfactant (a medicine that helps lungs work) to premature babies born between 27 and 35 weeks of pregnancy. It aims to reduce the need for more breathing support and avoid side effects.
Hackensack, New JerseyAges 6 months–8 months
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Respiratory Distress Syndrome trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for respiratory distress syndrome?
- Yes. Clin2 currently lists 200 recruiting respiratory distress syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a respiratory distress syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a respiratory distress syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Acute Respiratory Distress Syndrome
- Respiratory Distress Syndrome, Newborn
- Respiratory Distress Syndrome in Premature Infant
- Respiratory Distress Syndrome (Neonatal)
- Respiratory Distress
- Respiratory Distress Neonatal
- Respiratory Distress Syndrome, Adult
- Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.