Interleukin-6 blocker for stroke from skull artery narrowing
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether the drug tocilizumab (which blocks a protein called interleukin-6) can help prevent further strokes in people who have had a stroke or mini-stroke due to a narrowed artery inside the skull. If you are eligible, you would receive either tocilizumab or a placebo to see if it reduces your risk of another stroke.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older and had a recent stroke or transient ischemic attack (a mini-stroke) within the last 72 hours.
- The stroke or mini-stroke was caused by significant blockage (50-99% narrowing) in one of the arteries inside your skull.
- You have not received clot-busting medication or clot removal in the last 24 hours.
- You do not have serious heart conditions like atrial fibrillation, recent heart attack, or artificial heart valves.
- You do not have active infections, including tuberculosis, HIV, or hepatitis B, and no uncontrolled high blood pressure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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