Clin2
NCT06447701Possibly a fitNot yet recruiting

Anti-inflammatory drug for narrowing arteries in the brain

Brain DiseasesIschemic StrokeIschemiaStrokeCerebral InfarctionAtherosclerosis of ArteryAtheroscleroses, Intracranial

Treatments studied

Part of Brain & nervous system, Heart & circulation clinical trials.

This trial tests whether a drug that lowers inflammation can reduce the risk of another stroke in people with narrowing of a brain artery. The treatment is given after a mild stroke or mini-stroke.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
486 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 or older.
  • You had a mild stroke or a mini-stroke in the last 3 days.
  • Tests show that one of the main arteries in your brain is narrowed by 50% to 99%.
  • You have not had clot-busting medicine or a procedure to remove a clot in the last 24 hours.
  • You are willing to attend follow-up visits as needed.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07509645Recruiting· Phase 3
Testing a new drug with clot removal for severe back-of-the-brain stroke

This trial checks if adding an interleukin-6 receptor inhibitor (a drug that reduces inflammation) to standard emergency clot removal can improve recovery for people with a severe stroke affecting the back part of the brain (posterior circulation). It is for patients who need urgent treatment within 24 hours of symptom onset.

Huaibei, Anhui
NCT04701619Not yet recruiting
Immune response and stroke treatment outcomes

This study looks at how your immune system reacts to stroke treatments like clot-busting drugs or mechanical clot removal. The goal is to see if immune markers can predict recovery, which could help tailor future stroke care.

NCT02638701Recruiting· Phase 1/Phase 2
Infliximab for hard-to-treat brain blood vessel aneurysms

This Phase 1/2 trial tests infliximab, a medicine that calms inflammation, for dolichoectactic aneurysms in the vertebral/basilar brain blood vessels that usually cannot be treated with standard surgery or procedures. The goal is to see if it can improve safety and how the aneurysm behaves over time.

San Francisco, California
NCT07870681Not yet recruiting· Phase 2/Phase 3
Tocilizumab for acute ischemic stroke after clot removal

This trial studies whether giving an anti-inflammatory drug called tocilizumab after emergency clot removal improves recovery from a severe stroke caused by a blocked artery in the brain.

Aalborg
NCT07801638Recruiting
Anticoagulation plus tocilizumab for cerebral venous thrombosis

This trial tests a combination of blood thinners (anticoagulation) and a drug called tocilizumab, which targets inflammation, to treat acute cerebral venous thrombosis (a blood clot in a vein in the brain). It aims to see if this combined treatment improves recovery and reduces complications compared to blood thinners alone.

Beijing, Beijing Municipality
NCT06863480Recruiting· Phase 1
Trial of tocilizumab for bleeding stroke to prevent later strokes

This trial tests if a drug called tocilizumab (TYENNE) can reduce the risk of delayed strokes after a bleeding stroke from a ruptured aneurysm. It is for adults who had a specific type of brain bleed and need a drain to remove fluid.

Gainesville, Florida

Hear when a new Brain Diseases trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.