A trial of sonlicromanol for mitochondrial disease
Part of Bones, joints & muscles, Brain & nervous system, Genetic & congenital, Heart & circulation, Hormones & metabolism clinical trials.
This trial tests a new medicine, sonlicromanol, for people with a specific type of mitochondrial disease (caused by the m.3243A>G mutation) who also have chronic fatigue and muscle weakness. The goal is to see if it helps improve symptoms and daily function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older and have a mitochondrial disease caused by a specific genetic change (m.3243A>G).
- You have had constant fatigue for at least 3 months that is not due to another illness.
- You can do the '5 times sit to stand' test (stand up and sit down quickly 5 times) in 30 seconds or less.
- You do not have major heart problems, like serious irregular heartbeat or recent heart procedures.
- You do not have severe stomach or bowel issues that would affect how the study drug works.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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