Acetazolamide and Furosemide for Acute Heart Failure
Part of Heart & circulation clinical trials.
This trial tests whether adding an oral water pill (acetazolamide) to standard IV furosemide helps people with acute heart failure who have fluid overload. It aims to see if the combination improves outcomes better than furosemide alone.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have acute heart failure with signs of fluid overload (swelling, fluid in belly, or lungs).
- You are already taking at least 40 mg of furosemide (water pill) daily for at least a month.
- Your NT-proBNP level (a heart stress marker) is high (over 300 pg/mL or age-adjusted).
- You do not have a recent heart attack or unstable angina.
- Your kidney function is not very low (eGFR above 20).
- You are not pregnant, breastfeeding, or on dialysis.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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