Acetazolamide for heart failure to reduce fluid and symptoms
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests a new use of the drug acetazolamide (commonly used for other conditions) to help remove extra fluid and reduce weight in people with heart failure. It might help relieve symptoms like swelling and shortness of breath.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have heart failure (any type – reduced or preserved pumping function).
- You take a daily diuretic (water pill) like furosemide at a dose of at least 20 mg.
- You have been hospitalized or had an urgent visit for heart failure symptoms recently.
- You have a home weight scale that sends your weight to your care team.
- Your kidney function is not severely impaired.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether adding acetazolamide (a different type of water pill) to your current treatment helps remove extra fluid from your body more effectively when you are in the hospital for heart failure.
This study looks at how your kidneys handle salt and water when you're treated for acute heart failure in the hospital. Researchers want to understand which patients recover well from fluid buildup and which might need different treatment approaches.
This trial tests if using urine sodium levels to guide diuretic (water pill) dosing during hospital care for worsening heart failure can improve outcomes. The goal is to help doctors adjust treatment more effectively to clear extra fluid from the body.
This trial tests a new way to adjust diuretic (water pill) doses based on urine sodium levels in patients hospitalized for worsening heart failure. The goal is to improve fluid removal and get patients home sooner.
This trial tests a new way to manage fluid levels in people hospitalized for heart failure. It aims to help doctors adjust treatment to keep you from coming back to the hospital.
This trial tests whether adding an oral water pill (acetazolamide) to standard IV furosemide helps people with acute heart failure who have fluid overload. It aims to see if the combination improves outcomes better than furosemide alone.
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