Comparing two water pills for acute heart failure
Treatments studied
Part of Heart & circulation clinical trials.
This trial compares two different water pills (acetazolamide and metolazone) added to standard care for people hospitalized with acute heart failure who still have fluid buildup after an initial dose of IV furosemide. The goal is to see which works better to remove extra fluid.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are in the hospital for acute heart failure symptoms like trouble breathing or swelling.
- You can be enrolled in this study within 24 hours of arriving at the hospital.
- You have not received more than one dose of IV furosemide (a water pill) before entering the study.
- Your heart failure is not caused by certain types of heart muscle disease or valve problems.
- Your kidneys work well enough (eGFR above 20) and you are not on dialysis.
- You have not taken another diuretic (water pill) besides furosemide before the study starts.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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