Adding a Water Pill for Heart Failure in the Hospital
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests if adding a diuretic (water pill) called acetazolamide to usual care can help you get rid of extra fluid faster while you are in the hospital for worsening heart failure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are currently in the hospital for worsening heart failure and have signs of extra fluid in your body (like swelling in your legs, fluid in your belly, or fluid around your lungs).
- You do not have type 1 diabetes.
- Your kidneys are working well enough (no dialysis needed).
- Your blood pressure is not too low (above 90 mmHg). You are not in cardiogenic shock.
- You have not taken certain diabetes or water pills (for example, empagliflozin, dapagliflozin, or hydrochlorothiazide) in the last 2 days.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether adding acetazolamide or metolazone to standard treatment helps remove extra fluid better in people hospitalized for heart failure. It aims to find a safer and more effective option for managing fluid overload.
This trial tests whether adding an oral water pill (acetazolamide) to standard IV furosemide helps people with acute heart failure who have fluid overload. It aims to see if the combination improves outcomes better than furosemide alone.
This trial tests a device designed to safely remove extra fluid from patients hospitalized with worsening heart failure. It may help those who are not responding well to standard water pills (diuretics).
This trial tests if dapagliflozin or acetazolamide works better for people hospitalized with heart failure who have extra fluid in their body (congestion). The study will compare how well each medication helps remove fluid when used with standard IV diuretics.
This trial tests different water pill (diuretic) strategies for people hospitalized with acute heart failure and too much fluid. It is designed for patients who may not respond well to standard water pills, to find a more effective way to relieve symptoms.
This trial compares two different water pills (acetazolamide and metolazone) added to standard treatment to help remove excess fluid in people hospitalized with acute heart failure. The goal is to find which works better to ease symptoms and improve recovery.
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