Eye response study for new antidepressant treatment
Part of Mental health clinical trials.
This study looks at how your eyes respond to light (electrophysiological markers) to better understand how antidepressants work. If you join, your brain and eye activity will be measured before and after starting a new antidepressant, which may help doctors choose more effective treatments for depression in the future.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are an adult (18 or older) with a current episode of unipolar depression (not bipolar) diagnosed by a doctor.
- Your doctor has prescribed a specific type of antidepressant for this episode (either an SSRI like sertraline or fluoxetine, or an alpha-2 antagonist like mirtazapine), and you have not yet started it.
- You must be a native French speaker and covered by a French health insurance (like Sécurité Sociale).
- You are not at high risk of suicide, and you do not have other progressive psychiatric conditions (anxiety disorder is okay).
- You have no serious eye disease, no history of head trauma, epilepsy, or other neurological conditions.
- You do not have any implanted medical device (like a pacemaker) or open wounds where the eye-tracking equipment would be placed.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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