Study sleep-like brain signaling in major depression
Part of Mental health clinical trials.
This trial looks at how a specific brain receptor related to pain signals (nociceptin/orphanin FQ receptor) may be involved in depression. It may help researchers understand depression better by comparing people with current versus past (remitted) major depression.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 18 to 45 years old and able to write consent in English
- Use a smartphone (iPhone or Android) for daily moment-by-moment questions
- Be right-handed
- Not take any psychiatric medicines that affect mood for at least 2 weeks before joining
- Have no anxiety disorder in the last 2 months (for the depression groups in this study)
- Be able to have MRI scans safely (not unsafe for MRI in the screening)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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