Study of selinexor combo for returning brain lymphoma
Treatments studied
Part of Brain & nervous system, Cancer, Immune system & allergy clinical trials.
This trial tests a new combination of drugs (selinexor, temozolomide, and an immunotherapy) for people whose primary central nervous system lymphoma has come back or stopped responding to previous treatment. The goal is to see if this combination can help shrink or control the lymphoma.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have primary central nervous system lymphoma (a type of lymphoma that starts in the brain or spinal cord) that has returned or not responded to at least one prior treatment that included methotrexate.
- You can swallow oral tablets or capsules without difficulty.
- Your major organs (like bone marrow, liver, and kidneys) are working well enough, based on blood tests.
- You are not pregnant or breastfeeding, and you agree to use effective birth control during the study and for 6 months after the last dose.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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