Radiation to internal mammary lymph nodes for high-risk breast cancer after chemo
Part of Cancer, Skin clinical trials.
This trial tests whether giving radiation to the internal mammary lymph nodes (the lymph nodes behind your breastbone) can help women with high-risk breast cancer after they have had chemotherapy before surgery. It is for people whose cancer has spread to nearby lymph nodes despite chemotherapy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with invasive breast cancer (cancer that has spread into surrounding breast tissue).
- You have already received chemotherapy before your surgery (neoadjuvant chemotherapy).
- After chemotherapy, your cancer was found in the lymph nodes under your arm or above your collarbone.
- You have no cancer that has spread to distant parts of your body (like the lungs, liver, or bones).
- You have not had cancer in the lymph nodes behind your breastbone before starting treatment.
- You are willing to come for follow-up visits and have signed a consent form.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies whether some patients with early-stage breast cancer can safely skip a specific part of radiation to the inner chest (called internal mammary irradiation). It may reduce radiation side effects while still aiming to prevent the cancer from coming back.
This trial tests giving a focused, higher dose of radiation to the lymph nodes above the collarbone after breast cancer treatment. It is for patients whose cancer did not fully disappear from those nodes after pre-surgery chemotherapy, to see if extra radiation can help prevent recurrence.
This trial compares the benefits and risks of adding radiation therapy to the lymph nodes near the breast after surgery for people with breast cancer that has spread to a small number of lymph nodes. It may help prevent the cancer from coming back in those lymph nodes.
This trial looks at whether adding targeted radiation to lymph nodes after breast surgery can lower the chance of breast cancer coming back in people with higher-risk, node-negative disease. If you qualify, you may get a planned radiation approach designed for prevention, not treatment of spread.
This trial is testing whether radiation therapy to just the breast (not the lymph nodes) is safe and effective for women with early-stage, low-risk breast cancer. It aims to see if omitting the sentinel node biopsy is acceptable when the cancer has not spread to the lymph nodes.
This trial compares two ways of giving radiation to lymph node areas near the collarbone after surgery for invasive breast cancer. It aims to see which radiation approach works better and is safer for preventing cancer returning in these lymph nodes.
Hear when a new Breast cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.