Ketorolac for sickle cell pain crisis in children
Treatments studied
Part of Blood & lymphatic, Genetic & congenital clinical trials.
This trial tests a pain medicine called ketorolac (an NSAID) to see if it helps children with sickle cell disease who come to the emergency room or clinic with sudden, severe pain. If your child has sickle cell disease and is having an acute pain crisis, this study may be an option.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child has sickle cell disease (any type) and is having a sudden pain crisis
- Your child is being seen at the Dell Children's Emergency Department or hematology clinic
- Your child has not taken ibuprofen, naproxen, or similar NSAID pain medicine in the last 6 hours
- Your child does not have known kidney injury or sickle cell kidney disease
- Your child does not have any bleeding problems or allergy to NSAID medications
- Your child does not have chronic pain or unstable vital signs (like very low blood pressure)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if an intravenous medication called L-citrulline can help treat pain crises in children and young adults with sickle cell disease. Participants receive either the study drug or a placebo while in the hospital for a severe pain episode.
This trial tests an IV medication called L-citrulline for children, teens, and young adults (ages 6–21) with sickle cell disease who are having a sudden, severe pain crisis (called a vaso-occlusive crisis). The goal is to see if it helps relieve pain quickly.
This study tests whether a low-dose of ketamine (a pain medicine) can help children and young adults with sickle cell disease who are in a pain crisis. It aims to provide better pain relief while avoiding some side effects of standard painkillers.
This study looks at how children with sickle cell disease experience and manage pain crises, known as vaso-occlusive crises. The goal is to better understand these events to improve care for children living with this condition.
This trial tests when to start ketamine for children and teens with sickle cell disease who are in pain. It aims to find the best timing to help reduce pain in the emergency room or infusion clinic.
This trial tests whether taking ketamine by mouth can help treat “vaso-occlusive” pain episodes that may require hospital admission. If it works, it could offer an easier way to manage severe pain during sickle cell crises.
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