CAR-T cell therapy for relapsed or resistant B-cell leukemia
Treatments studied
Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.
This trial tests a new CAR-T cell therapy that targets a protein called CD19 on leukemia cells. It's designed for people with relapsed or refractory B-cell acute lymphoblastic leukemia (a type of blood cancer) that hasn't responded to standard treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older.
- You have B-cell acute lymphoblastic leukemia (a type of blood cancer) that either did not respond to first treatment or has come back after remission.
- Your leukemia cells must show a protein called CD19 (a lab test confirms this).
- You must have some measurable disease in the bone marrow (at least 5% blasts).
- You must be reasonably healthy (able to do most daily activities, with good heart, kidney, liver, and lung function).
- You must not have had another CAR-T or gene-modified cell therapy before.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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