Colchicine to prevent strokes after brain bleed
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests if a drug called colchicine can reduce the risk of future strokes and improve recovery after a recent brain bleed (intracerebral hemorrhage). It is for people who also have heart or blood vessel disease or multiple risk factors like high blood pressure or diabetes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have had a brain bleed within the last 3 days
- You have a history of heart, leg, or neck artery disease, or at least 2 risk factors like age 60+, high blood pressure, diabetes, smoking, or kidney disease
- Your brain bleed was not caused by injury, a tumor, or a bleeding disorder
- The bleed on your last scan is not larger than 60 mL (about the size of a tennis ball)
- You are awake enough to participate and are not on a breathing machine
- You do not have severe liver or kidney disease, active inflammatory bowel disease, or chronic diarrhea
- You are not pregnant or breastfeeding, and have no known allergy to colchicine
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether the anti-inflammatory drug colchicine can help prevent a second stroke in people who recently had a mild to moderate ischemic stroke. If you had a stroke 1 to 4 weeks ago and are between 18 and 80 years old, you may be able to join.
This Phase 3 study tests whether low-dose colchicine added to ticagrelor (a blood-thinning medicine) helps prevent another ischemic stroke in people whose first stroke was caused by clogged arteries. It aims to lower the risk of repeat stroke after recovery from a recent event.
This trial tests whether a low dose of the anti-inflammatory drug colchicine can help people who have recently had a heart attack or unstable angina. It aims to see if colchicine reduces the risk of future heart problems.
This trial tests whether colchicine (a medicine used for gout) can help prevent heart problems after a stent procedure (PCI). It's for people who are in the hospital getting a stent and follow standard heart care.
This clinical trial tests whether a medication called cilostazol can help the body reabsorb a brain bleed (intracerebral hemorrhage) more quickly. It is for adults with a small bleed in a specific part of the brain (thalamus or basal ganglia) who are otherwise in good health.
This trial tests whether the drug colchicine can reduce the chance of developing atrial fibrillation (an irregular heart rhythm) after open-heart surgery. If it works, it could help you recover more smoothly.
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