Clin2
NCT06591910Possibly a fitNot yet recruiting

Serplulimab plus chemo for stage III lung cancer

Unresectable Stage III Non-small-cell Lung Cancer

Part of Cancer, Lungs & breathing clinical trials.

This trial tests whether adding an immunotherapy drug (Serplulimab) to chemotherapy before surgery can help people with advanced stage III non-small cell lung cancer that cannot be removed. It aims to shrink the tumor and improve outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
50 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You are 18 years or older.
  • You have stage III non-small cell lung cancer that cannot be surgically removed.
  • You have not had prior cancer treatment like chemotherapy, radiation, or targeted therapy.
  • You are in good enough health to walk and take care of yourself (ECOG 0 or 1).
  • You have at least one tumor that can be measured on a scan.
  • You agree to use birth control if you or your partner could become pregnant.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07408635Recruiting· Phase 2
New Immunotherapy Plus Chemotherapy Before Lung Cancer Surgery

This trial tests a new combination of an immunotherapy drug (IBI363) plus chemotherapy before surgery in people with Stage III lung cancer that can't be removed at first. The goal is to shrink the tumor so it can be surgically removed.

Shanghai
NCT05837052Recruiting· Phase 2
Serplulimab plus chemo after initial treatment for lung cancer

This Phase 2 study looks at how safe and effective serplulimab (an immune medicine) combined with chemotherapy is when used as a “conversion” plan—first shrinking lung cancer, then trying to remove the main tumor with surgery. It may help some people who are not initially good candidates for surgery or focused radiation to become eligible after treatment.

Hangzhou, Zhejiang
NCT07264647Recruiting· Phase 2
Chemo-immunotherapy before surgery for stage III lung cancer

This trial tests combining chemotherapy with immunotherapy before surgery for people with stage III non-small cell lung cancer that has a PD-L1 level of 1% or higher. The goal is to see if this approach can improve outcomes.

Rome, Roma (RM)
NCT05766800Recruiting· Phase 2
PD-1 plus chemotherapy before surgery for advanced lung cancer

This trial studies whether giving a PD-1 antibody together with standard chemotherapy before surgery can improve outcomes for people with stage IIIB–IIIC non-small cell lung cancer. It aims to shrink or control the cancer and make treatment before surgery more effective.

Shanghai
NCT07647094Recruiting· Early Phase 1
Chemotherapy plus immunotherapy for advanced squamous lung cancer

This trial tests a combination of three drugs—two chemotherapy medications (carboplatin and nab-paclitaxel) plus an immunotherapy drug (serplulimab)—as a first-line treatment for advanced squamous cell non-small cell lung cancer. The goal is to see if this combination works better than standard treatment and is safe for patients who haven't received prior systemic cancer treatment.

Quzhou, Zhejiang
NCT06962189Not yet recruiting· Phase 2
Sintilimab plus chemo for lung cancer before surgery

This trial tests a combination of chemotherapy and an immunotherapy drug called sintilimab to shrink unresectable stage IIIB-IIIC non-small cell lung cancer, making it possible to remove it with surgery. The goal is to see if this approach can help patients who aren't candidates for surgery now become candidates later.

Hear when a new Unresectable Stage III Non-small Cell Lung Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.