Clin2
NCT07264647Possibly a fitRecruiting

Chemo-immunotherapy before surgery for stage III lung cancer

Stage III NSCLC

Treatments studied

Part of Cancer, Lungs & breathing clinical trials.

This trial tests combining chemotherapy with immunotherapy before surgery for people with stage III non-small cell lung cancer that has a PD-L1 level of 1% or higher. The goal is to see if this approach can improve outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
30 people
Ages
18 years to 99 years
Study type
Interventional

Who can take part

  • You have stage III non-small cell lung cancer that hasn't spread to other parts of the body.
  • Your tumor has a PD-L1 level of 1% or higher (a protein that may help the immunotherapy work).
  • You do not have certain gene changes (EGFR, ALK, ROS1, or RET) in your tumor.
  • You are healthy enough to have surgery and chemotherapy, with good lung and organ function.
  • You have not had any previous treatment for this lung cancer, including chemotherapy or radiation.
  • You are 18 years or older and can give informed consent.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06591910Not yet recruiting
Immunotherapy and chemotherapy for stage III lung cancer

This trial tests whether giving a combination of an immunotherapy drug (serplulimab) and chemotherapy before any surgery can help shrink tumors in people with stage III lung cancer that can't be removed. The goal is to make the cancer easier to treat and improve outcomes.

NCT05891080Not yet recruiting· Phase 2
Immunotherapy plus chemo before surgery for stage III lung cancer

This trial tests a new combination of drugs given before surgery for stage III lung cancer. It aims to shrink the tumor to make surgery more effective and possibly improve your chances of a cure.

NCT04728724Recruiting· Phase 2
Check immune treatment before surgery for stage III lung cancer

This Phase 2 trial tests an “immunotherapy” medicine given before surgery for stage III non-small cell lung cancer. The goal is to shrink the cancer and make curative surgery more successful while monitoring safety and response.

Shanghai
NCT06614231Not yet recruiting· Phase 2
Immunotherapy plus chemotherapy for stage III lung cancer

This trial combines an immunotherapy drug (tislelizumab) with chemotherapy before surgery to try to shrink the tumor and possibly make surgery possible later. The goal is to improve outcomes for people with stage III non-small cell lung cancer that is not removable at diagnosis.

NCT07538193Not yet recruiting
Immunotherapy plus chemo before surgery for stage III lung cancer

This trial tests whether giving a combination of two immunotherapy drugs with chemotherapy before surgery can help shrink stage III lung cancer and improve outcomes. It is for people whose cancer has spread to lymph nodes in the chest but can still be removed with surgery.

Xi'an, Shannxi
NCT06908733Not yet recruiting· Phase 2
Immunotherapy and surgery for stage 3 lung cancer

This study tests a new approach: giving an immunotherapy drug (tislelizumab) plus chemotherapy before surgery or radiation for advanced lung cancer that has spread to chest lymph nodes. The goal is to shrink the cancer first, then remove or treat it, to improve chances of long-term control.

Hear when a new Stage III NSCLC trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.