Clin2
NCT06592261Possibly a fitCompleted

Insulin suppression test for weight groups

Insulin ResistanceHyperinsulinemiaObesityHealthy

Part of Hormones & metabolism clinical trials.

This study tests a new way to measure how the body handles insulin in people with different body weights. It may help researchers understand insulin resistance better.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
20 people
Ages
18 years to 65 years
Study type
Interventional

Who can take part

  • You must have a body mass index (BMI) between 18-25 or 30-45.
  • You must be able to understand English or Spanish.
  • Your fasting insulin level must be in a specific range (4-10 or 13 or higher) based on your weight group.
  • You must not have diabetes or prediabetes (like high blood sugar or A1c).
  • You must not be taking most diabetes medicines (except metformin) or certain heart medicines.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06558422Not yet recruiting· Phase 1
Study of insulin resistance using a pancreatic clamp

This study looks at how the body handles insulin in people who are insulin resistant. You will receive a special procedure called a pancreatic clamp to measure insulin sensitivity, which may help researchers understand and treat insulin resistance better.

New York, New York
NCT07403604Recruiting· Phase 1
Lowering Insulin to Reduce Fat Buildup in the Liver

This study tests if lowering insulin levels can reduce fat buildup in the liver for people with a fatty liver condition called MASLD. It's looking for adults who are overweight and have early signs of insulin resistance but not diabetes.

New York, New York
NCT06065930Recruiting
Adaptive Mechanisms in Grown-Up Obesity (AMIGROS)

This study looks at how the body adapts in people with different body weights and insulin sensitivity. It compares lean adults and those with obesity, with or without insulin resistance, to understand metabolism better. Participation involves a few visits and some tests.

Gothenburg, Region Vastra Gotaland
NCT07516509Recruiting
How muscle cells respond to blood sugar in different body types

This research study examines how muscle cells handle blood sugar differently depending on whether someone is lean or has obesity, and whether their body resists insulin. Researchers will take small muscle samples to understand the genetic differences, which may help develop better treatments for insulin resistance and metabolic health.

Orlando, Florida
NCT07653464Not yet recruiting· Early Phase 1
Insulin effects on blood vessels in obesity

This study looks at how insulin affects blood vessels in people with obesity compared to healthy weight adults. It may help understand why obesity increases heart disease risk.

Columbia, Missouri
NCT07854886Not yet recruiting
Brain response to a diabetes drug in healthy weight and obesity

This study looks at how a medication that mimics a natural gut hormone affects brain activity related to appetite in people with healthy weight or obesity. It may help researchers find new ways to treat obesity.

Copenhagen

Hear when a new Insulin Resistance trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.