Insulin's effects on blood vessels in obesity
Part of Hormones & metabolism clinical trials.
This study looks at how insulin affects blood vessels and the brain in people with obesity and insulin resistance, compared to healthy-weight individuals. It may help explain why obesity raises heart and blood vessel risks.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You either have obesity (BMI 30–45 with a large waist and insulin resistance) or are a healthy weight (BMI 18–25).
- You are not pregnant or breastfeeding.
- You do not have diabetes, polycystic ovary syndrome, heart disease, or active cancer.
- You do not smoke or use nicotine products.
- You do not have metal implants or claustrophobia (since you need an MRI).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how very small particles in the body (“extracellular vesicles”) relate to insulin action and how the body handles sugar. It may help researchers understand why some people have better or worse insulin responses.
This study tests whether a GLP-1 receptor agonist (a type of diabetes medicine) changes how the brain responds to insulin in people with different body sizes. It may help understand if this drug can improve brain function related to insulin.
This study follows adults over time to understand how weight and body chemistry relate to insulin resistance. It may help researchers learn why insulin resistance happens and what could prevent or improve it.
This study looks at how differences in insulin resistance may change how the liver makes triglycerides (a type of blood fat). It may help researchers understand why some people have higher triglycerides and how to target them better.
This research study examines how muscle cells handle blood sugar differently depending on whether someone is lean or has obesity, and whether their body resists insulin. Researchers will take small muscle samples to understand the genetic differences, which may help develop better treatments for insulin resistance and metabolic health.
This study looks at how insulin resistance affects tiny heart arteries in people who have chest pain and signs of heart stress on tests, but do not have major blockages in their heart arteries. It aims to understand why some people have heart symptoms even when their main arteries appear clear.
Hear when a new Obesity (BMI>30) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.