Clin2
NCT06609668Possibly a fitRecruiting

Thrombomodulin blood test to rule out giant cell arteritis in PMR

Giant Cell Arteritis (GCA)Polymyalgia Rheumatica (PMR)

Part of Bones, joints & muscles, Brain & nervous system, Heart & circulation, Immune system & allergy, Skin clinical trials.

This study tests whether a blood test for a protein called thrombomodulin can help rule out giant cell arteritis (a blood vessel inflammation) in people with polymyalgia rheumatica. It involves a blood draw and a one-time imaging scan to look at your blood vessels.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
78 people
Ages
50 years and older
Study type
Observational

Who can take part

  • You are over 50 years old.
  • You have been diagnosed with polymyalgia rheumatica (PMR) based on specific symptoms like morning stiffness and certain blood test results.
  • You have not taken any steroids or immune-suppressing drugs in the past month.
  • You do not have an active infection, cancer, or other autoimmune disease (like rheumatoid arthritis).
  • You are willing to have a vascular imaging scan (CT or PET) to check for giant cell arteritis.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05479448Recruiting
Tracking what predicts response in new PMR or GCA

This study looks at people newly diagnosed with polymyalgia rheumatica (PMR) or giant cell arteritis (GCA) and uses their health and treatment information to learn what predicts how well treatment works. It may help your care in the future by improving which patients respond best and how.

Basel
NCT07010484Recruiting
New imaging tests for polymyalgia rheumatica

This trial tests if new imaging methods can help diagnose and treat polymyalgia rheumatica (PMR). It may be for you if you're over 50, have pain in your shoulders or hips, and haven't taken steroids for PMR in the last 2 months.

Aarhus
NCT07748195Not yet recruiting
DNA methylation in polymyalgia rheumatica

This study looks at blood markers related to DNA changes in people with polymyalgia rheumatica (PMR). It aims to better understand the condition and may help guide future treatments.

NCT07150000Recruiting
Rheumatic disease research study for patients and healthy volunteers

This study is for people with certain rheumatic conditions (like arthritis, lupus, or vasculitis) and for healthy volunteers. It aims to learn more about these diseases and improve how they are treated.

Bonn, North Rhine-Westphalia
NCT07269938Not yet recruiting
B-cell study for giant cell arteritis and related conditions

This study looks at immune cells called B-cells in people with giant cell arteritis (a condition causing inflammation in blood vessels) and other immune disorders, to see if targeting these cells could be a new treatment. It involves imaging and blood tests.

Edinburgh, City Of Edinburgh
NCT06957002Not yet recruiting· Phase 2
Bosentan for giant cell arteritis

This trial tests whether a drug called bosentan, which is usually used for other conditions, can help calm the inflammation in giant cell arteritis and reduce symptoms. You would take it in addition to your usual treatment, and it might help lower the dose of steroids you need.

Paris

Hear when a new Polymyalgia Rheumatica (PMR) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.