Pre-surgery treatment comparison for non-small cell lung cancer
Treatments studied
Part of Cancer, Lungs & breathing clinical trials.
This trial compares two treatment approaches before surgery for non-small cell lung cancer (NSCLC): radiation plus immunotherapy versus chemotherapy plus immunotherapy. The goal is to see which combination works better to shrink the tumor before it is removed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have non-small cell lung cancer (NSCLC) that is stage IB, II, or III (N2) and your doctor plans to remove it with surgery.
- Your tumor is measurable on imaging scans (like CT or MRI).
- Your tumor has been tested for PD-L1 (a protein that helps the immune system attack cancer) and the result is known.
- Your tumor does not have EGFR mutation or ALK fusion (specific gene changes that might affect treatment choice).
- You have not had any prior treatment for your lung cancer.
- You are 18 or older, in good physical condition (ECOG 0 or 1), and have adequate organ function (kidneys, liver, bone marrow).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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