Comparing three devices to clear lung blockages in ventilated patients
Part of Lungs & breathing clinical trials.
This trial tests three different machines that help clear mucus from the lungs of patients on breathing machines. The goal is to treat collapsed lung areas (atelectasis) caused by blocked airways.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been on a breathing machine for at least 48 hours.
- You have a lung collapse (atelectasis) confirmed by a scan or ultrasound.
- You are in the hospital and need help clearing mucus from your airways.
- You are willing to participate and sign a consent form (or have a guardian do it).
- You do not have certain serious conditions, such as severe obesity (BMI over 40), major chest deformities, or unstable blood pressure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial looks at a part of breathing machines called 'dead space' in adults having planned surgery under general anesthesia. The goal is to learn more about how the lungs work during controlled breathing.
This trial tests a breathing treatment called Oscillation and Lung Expansion (OLE) therapy. It is for people on a breathing machine who have a collapsed area in the lung (atelectasis) and a lot of phlegm. The goal is to help open the lungs and clear mucus more easily.
This study tests two breathing treatments—ventilator hyperinflation and chest vibration—to see which works better for clearing mucus and improving lung function in people who have been on a breathing machine for 2 to 7 days.
This trial tests a device called MetaNeb that delivers high-frequency vibrations to help clear mucus and open collapsed air sacs in the lungs. It is designed for patients in the ICU who are awake, alert, and have trouble breathing or need extra oxygen.
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