Comparing MitraClip and PASCAL for mitral valve repair
Part of Heart & circulation clinical trials.
This trial compares two devices (MitraClip and PASCAL) for repairing a leaky mitral valve (mitral regurgitation). The goal is to see which device works better in a wide range of patients who need this type of repair.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You are willing and able to give written consent
- A heart team has recommended that you get a procedure called M-TEER (mitral valve transcatheter edge-to-edge repair)
- You do not have mitral stenosis (a stiff, narrow mitral valve)
- You are not in cardiogenic shock or unstable at the time of the procedure
- You do not have an active infection of the heart valve (endocarditis) and you are not in another interventional heart study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests Valveclip, a catheter-based way to repair a mitral valve that is leaking badly. It may help people who are high-risk for open surgery by aiming to reduce the leak with a less invasive approach.
This study tests a new clip procedure (CardioClip) to repair a leaky mitral valve in people with heart failure. It aims to see if the clip can improve symptoms and heart function.
This trial tests a minimally invasive procedure to fix a leaky mitral valve in people with ATTR-CM. The procedure, called edge-to-edge repair, uses a catheter to clip the valve, which may improve symptoms and quality of life.
This study is testing a new assist system to help doctors perform a minimally invasive procedure (MitraClip) that clips the leaky mitral valve without open-heart surgery. It is for people with severe mitral regurgitation who cannot safely have surgery or choose not to.
This trial tests a clip-based procedure (TEER) to fix a severe leak in the mitral valve for people who have symptoms or heart changes but are at low to medium risk for surgery. The goal is to see if this less invasive option works well and is safe.
This registry study follows people who have a severely leaky mitral heart valve and receive MitraClip, a procedure that repairs the valve through the skin. It helps doctors learn how well this treatment works over time for different patients.
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