Comparing MitraClip and PASCAL for mitral valve repair
Part of Heart & circulation clinical trials.
This trial compares two devices (MitraClip and PASCAL) for repairing a leaky mitral valve (mitral regurgitation). The goal is to see which device works better in a wide range of patients who need this type of repair.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You are willing and able to give written consent
- A heart team has recommended that you get a procedure called M-TEER (mitral valve transcatheter edge-to-edge repair)
- You do not have mitral stenosis (a stiff, narrow mitral valve)
- You are not in cardiogenic shock or unstable at the time of the procedure
- You do not have an active infection of the heart valve (endocarditis) and you are not in another interventional heart study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests Valveclip, a catheter-based way to repair a mitral valve that is leaking badly. It may help people who are high-risk for open surgery by aiming to reduce the leak with a less invasive approach.
This study tests a new clip procedure (CardioClip) to repair a leaky mitral valve in people with heart failure. It aims to see if the clip can improve symptoms and heart function.
This trial studies whether the MitraClip procedure can improve outcomes for people with advanced heart failure caused by significant leakage of the mitral valve. It focuses on people who still have severe symptoms and poor quality of life despite the best available heart medications.
This study looks at how well a clip (MitraClip G4) fixes a leaky heart valve in people with heart failure. If you are scheduled for this procedure, joining may help doctors learn more about the benefits of the clip.
This study tracks how well the newest MitraClip G5 device works when used to repair a leaky mitral valve in your heart. By collecting information from patients like you, researchers can learn what works best and help future patients.
This study is testing a new assist system to help doctors perform a minimally invasive procedure (MitraClip) that clips the leaky mitral valve without open-heart surgery. It is for people with severe mitral regurgitation who cannot safely have surgery or choose not to.
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