Stem cell treatment for hard-to-control epilepsy
Treatments studied
Part of Brain & nervous system clinical trials.
This trial tests a new treatment made from stem cells (called a secretome) given through an IV to see if it is safe and helpful for people with epilepsy that does not improve with standard medicines. It is for adults ages 18 to 60 whose seizures are not controlled by at least two anti-seizure drugs.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 60 years old.
- You have been diagnosed with epilepsy by a neurologist and have had at least 6 seizures in the last year.
- Your seizures are not controlled by at least two different epilepsy medicines you have taken for 12 months or more.
- You are generally healthy, not pregnant or breastfeeding, and do not have other serious brain diseases or uncontrolled mental health conditions.
- You have not had epilepsy surgery or a stroke, and do not have severe allergic reactions, autoimmune diseases, or major organ problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial is testing if injecting stem cells from a donor during deep brain stimulation (DBS) surgery can help control seizures better than DBS alone. It is for adults with epilepsy that does not respond to medicines.
This Phase 2 trial tests SPN-817 in adults whose seizures are still not well controlled despite trying multiple seizure medicines. It targets people with a specific type of brain finding called focal cortical dysplasia and looks at safety/tolerability and seizure outcomes over several weeks.
This early-stage trial tests whether transplanting special cells (UX-GIP001) into the brain can reduce seizures in people with drug-resistant epilepsy affecting the mesial temporal lobe—a common seizure origin that doesn't respond well to medications. The goal is to evaluate safety and whether this approach helps control seizures.
This trial tests a personalized brain stimulation method (transcranial electrical stimulation) to reduce seizures in children with hard-to-control partial epilepsy. It aims to find the best stimulation spot and settings for each patient by using advanced brain scans.
This study tests a personalized, non-invasive brain stimulation method called tDCS for people with drug-resistant epilepsy that starts in one part of the brain. It aims to reduce seizures in those who cannot have surgery or have not been helped by surgery.
This study tests a new type of brain stimulation called temporal interference to help people with epilepsy that hasn't responded well to medications. Researchers want to see if this approach can reduce seizures and improve thinking or memory problems.
Hear when a new Epilepsy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.