Cord blood stem cell transplant for aplastic anemia
Part of Blood & lymphatic clinical trials.
This study tests whether adding umbilical cord blood to a stem cell transplant from a half-matched donor can improve outcomes for people with severe aplastic anemia or related bone marrow failure diseases.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 6 and 75 years old.
- You have been diagnosed with severe aplastic anemia, transfusion-dependent non-severe aplastic anemia, or paroxysmal nocturnal hemoglobinuria (PNH) with bone marrow failure.
- Your doctor has said a stem cell transplant is a suitable treatment for you.
- You or your legal guardian understand the study and agree to join by signing a consent form.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new way of using a mix of donor stem cells (from a half-matched family member and a cord blood unit) to treat aplastic anemia, a condition where the bone marrow stops making enough blood cells. The goal is to see if this transplant approach is safe and helps rebuild healthy blood cells.
This trial tests a new type of transplant using donated cord blood for adults with aplastic anemia that has not improved with standard treatments. It aims to see if the transplant is safe and effective.
This trial tests a new way to treat severe aplastic anemia by combining a stem cell transplant from a half-matched donor with special stem cells from umbilical cord blood. The goal is to help your body make healthy blood cells again.
This trial tests whether an early bone marrow transplant from a half-matched family member or an unrelated donor can help people with severe aplastic anemia. It aims to restore the body's ability to make healthy blood cells.
This trial tests two different sources of donor cells for a transplant in patients with severe aplastic anemia (a condition where the bone marrow stops making enough blood cells). The study compares using cells from blood alone versus cells from both bone marrow and blood, to see which approach works better.
This study is testing whether a stem cell transplant (from a matched relative, unrelated donor, or half-matched donor) can help adults aged 40–60 with severe aplastic anemia that didn't get better or came back after standard treatments.
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