Stem cell transplant with cord cells for severe aplastic anemia
Part of Blood & lymphatic clinical trials.
This trial tests a new way to treat severe aplastic anemia by combining a stem cell transplant from a half-matched donor with special stem cells from umbilical cord blood. The goal is to help your body make healthy blood cells again.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 6 and 60 years old.
- You must have severe aplastic anemia or very severe aplastic anemia as diagnosed by a doctor.
- You must not have any serious lung, heart, liver, or kidney problems or an uncontrolled infection.
- You must be well enough to carry out daily activities (ECOG score 0 to 2).
- You cannot have Fanconi anemia or other inherited forms of bone marrow failure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial studies using a donor's blood stem cells (from bone marrow or blood) for a transplant in people with severe aplastic anemia, a condition where the bone marrow stops making enough blood cells. The goal is to see if using a mix of both types of cells is better than just blood cells alone.
This trial tests whether an early bone marrow transplant from a half-matched family member or an unrelated donor can help people with severe aplastic anemia. It aims to restore the body's ability to make healthy blood cells.
This study tests a special cord blood transplant that may help your body start making blood cells faster than a regular transplant. It is for people with severe aplastic anemia or related bone marrow failure who have not gotten better with other treatments.
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This trial tests whether giving children with aplastic anemia a transplant using a matched unrelated donor (a bone marrow donor who is not a family member) can help treat their condition. It aims to see if this approach is effective and safe for children who qualify.
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