Pain relief after knee arthroscopy: numbing injection with added medication
Treatments studied
Part of Pain clinical trials.
This trial tests whether adding dexmedetomidine to a numbing injection (bupivacaine) inside the knee joint provides better pain relief after arthroscopic ACL reconstruction. It aims to help patients recover more comfortably after surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You are in good general health (classified as ASA I or II).
- You are scheduled for anterior cruciate ligament (ACL) reconstruction through knee arthroscopy (keyhole surgery).
- You do not have kidney failure, liver failure, heart disease, high blood pressure, or diabetes.
- You do not have a bleeding disorder or an allergy to the study drugs (dexmedetomidine or bupivacaine).
- You have not taken NSAIDs or other painkillers in the 24 hours before surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests whether adding a sedative medicine (dexmedetomidine) to the standard numbing injection around the knee can improve pain control after total knee replacement. It might help you have less pain and need fewer opioids.
This trial tests whether adding fentanyl or dexmedetomidine to a standard numbing medicine (bupivacaine) provides better pain relief after knee surgery. It may help find the best option for patients undergoing knee procedures like total knee replacement or ACL repair.
This trial tests a combination of two pain-relief methods after total knee replacement: a spinal injection and a nerve block in the thigh. It aims to provide better pain control during and after surgery.
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This trial tests adding a medicine called dexmedetomidine to the numbing IV used during knee surgery. It aims to see if it provides better pain relief after surgery under spinal anesthesia.
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