Pancreas-Liver Communication in Teens with Obesity
Part of Hormones & metabolism clinical trials.
This study looks at how the pancreas and liver talk to each other in teens with obesity. It may help understand why some teens develop diabetes or fatty liver.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 12 and 16 years old.
- You have obesity (BMI above the 97th percentile for your age and sex).
- You don't have diabetes with certain immune markers (autoantibodies).
- You don't have any known liver disease besides fatty liver (NAFLD).
- You haven't taken any diabetes medications (like insulin or metformin) in the last 2 weeks.
- You are not taking any medication that affects liver function.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a personalized nutrition plan can help stabilize blood sugar in adolescents with obesity. If blood sugar levels are steadier, teens may feel fuller after meals, which could support healthier eating habits.
This study looks at how metabolism works in children and teens who have (or do not have) nonalcoholic fatty liver disease (NAFLD), a condition where fat builds up in the liver. Participants may include healthy-weight controls, obese controls without NAFLD, and kids with NAFLD who are already scheduled for a liver biopsy for clinical reasons.
This study looks at how metabolism and inflammation relate to diabetes risk in teenagers. It may help researchers understand why some teens develop type 2 diabetes.
This study looks for special markers in the blood that can detect fatty liver in teenage girls with PCOS. It aims to find a non-invasive way to identify early liver problems.
This study uses a special ultrasound technique (eco-elastography) to measure fat inside the pancreas and see how it relates to metabolic syndrome and the cells that produce insulin. It might help understand why some people develop diabetes or other metabolic issues.
This study tests a new, non-invasive way to diagnose a type of fatty liver disease (MASLD) in children with obesity. It aims to find simple blood or imaging markers that can detect the condition without a liver biopsy.
Hear when a new Type 2 Diabetes Mellitus in Obese trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.