Atorvastatin to protect the heart during leukemia or lymphoma treatment
Part of Blood & lymphatic, Cancer, Heart & circulation, Immune system & allergy, Injuries & trauma clinical trials.
This study tests whether taking atorvastatin, a common cholesterol-lowering drug, can protect the heart from damage caused by chemotherapy in people with acute myeloid leukemia or non-Hodgkin lymphoma. If you are about to start or currently receiving certain chemotherapy regimens, this trial may help reduce the risk of heart problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are over 18 years old
- You have acute myeloid leukemia treated with the 3+7 chemotherapy regimen or non-Hodgkin lymphoma treated with the CHOP regimen
- Your heart function is normal or near-normal, with an ejection fraction of 60% or higher
- You are not pregnant or breastfeeding
- You agree to participate in the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether common heart medicines (statins or ACE-inhibitors) can protect the heart during cancer radiation therapy. It is for adults who are about to start chest radiation and have not taken these drugs before.
This trial tests if a heart-protecting drug (dexrazoxane) can prevent heart damage in people getting chemotherapy for certain types of large B-cell lymphoma. It is for patients who already have heart risk factors or a history of heart failure.
This trial tests whether taking a statin (a cholesterol-lowering medicine) during immunotherapy for melanoma can prevent heart problems. It may help protect your blood vessels while you receive cancer treatment.
This Phase 2 study tests whether a blood-pressure medicine plan (a beta blocker plus lisinopril) can protect the heart in people newly diagnosed with acute myeloid leukemia (AML) who are starting anthracycline chemotherapy. It looks at heart safety by requiring a good heart scan before treatment and careful medication eligibility.
This Phase 3 study tests whether taking atorvastatin (a cholesterol-lowering medicine) can improve outcomes for women with estrogen-receptor–positive breast cancer. It may help by affecting cancer-related pathways and reducing risk of recurrence or progression.
This study helps people with newly diagnosed acute myeloid leukemia (AML) by closely monitoring their heart health during chemotherapy. It aims to detect any early heart problems caused by treatment so they can be managed sooner.
Hear when a new Leukemia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.