Neck lymph surgery safety test for Alzheimer's patients
Part of Brain & nervous system, Mental health clinical trials.
This trial tests a neck surgery (cervical LVA) to see if it is safe and might help Alzheimer's patients by improving brain waste drainage. You may be eligible if you have a confirmed Alzheimer's diagnosis and a positive amyloid PET scan.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a confirmed diagnosis of Alzheimer's disease from a doctor and a psychiatrist.
- You need a positive amyloid PET scan, which shows amyloid plaques in your brain.
- You must be 18 years or older and willing to sign a consent form (you or your legal representative).
- You cannot have had prior neck lymph node surgery, nasopharyngeal surgery, or brain surgery.
- You cannot have thyroid disease, chronic heart failure, or severe heart/lung problems that make anesthesia risky.
- You must not be allergic to shellfish or iodine, since the surgery uses a dye (ICG) related to iodine.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a neck surgery (lymphaticovenous and lymph node-to-vein anastomosis) to see if it improves symptoms in people with Alzheimer's disease linked to a brain lymphatic circulation disorder. It focuses on those with moderate-stage Alzheimer's and confirmed amyloid buildup.
This study tests a surgery that connects tiny lymph vessels in the neck to improve brain drainage in people with moderate Alzheimer's. It aims to see if this can slow down memory loss.
This trial tests a new surgery on neck lymph vessels to see if it helps people with Alzheimer's. It is for patients aged 60 to 80 with mild to severe Alzheimer's who have had the diagnosis for over a year.
This study tests a surgical procedure to connect lymph vessels in the neck to veins, which may help clear waste from the brain in people with mild cognitive impairment or mild to moderate Alzheimer's disease. It is for patients who have not improved after at least 3 months of standard care.
This study tests a new surgery called cervical lymphatic bypass to see if it can help people with Alzheimer's disease. The surgery creates a new connection in the neck to improve drainage of waste from the brain, which may slow memory loss.
This study tests a new surgery to improve drainage in the neck that might help clear waste from the brain in people with Alzheimer's disease. The goal is to see if it can slow down memory and thinking problems.
Hear when a new Alzheimer's Disease (AD) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.