Daily dornase alfa after aneurysm bleed for better recovery
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether giving dornase alfa daily for up to 14 days after a subarachnoid hemorrhage (a type of bleeding around the brain from a burst aneurysm) helps people be more independent 6 months later. It is for people whose bleeding started less than 48 hours ago and whose aneurysm has already been treated.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have had a subarachnoid hemorrhage (bleeding around the brain) from a burst aneurysm.
- Your symptoms started less than 48 hours ago.
- The aneurysm has been treated (surgically or with a catheter) in the last 24 hours with no complications.
- A CT scan before treatment showed significant bleeding (Fisher score higher than 1).
- Your kidneys work well (no severe kidney disease).
- You do not have severe infections or known allergies to dornase alfa or related products.
- You were independent before the hemorrhage (no significant disability).
- You are not pregnant, breastfeeding, or participating in another drug/device trial.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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