Aortic stiffness imaging in aortic coarctation
Part of Genetic & congenital, Heart & circulation clinical trials.
This study uses heart MRI (CMR) to measure how stiff the aorta is in people with aortic coarctation (a narrowing of the main artery). It aims to see if stiffness relates to the severity of the narrowing, which may guide treatment decisions.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 14 years or older
- You must have aortic coarctation, either present from birth or recurring after a previous repair
- The pressure difference across the narrowed area must be at least 20 mm Hg (measured during a heart catheterization)
- You must weigh at least 20 kg (about 44 pounds)
- Your heart's pumping function (ejection fraction) must be normal
- You must not have other significant heart or genetic conditions, and you must be able to have an MRI (no metal implants, no severe claustrophobia)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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