Comparing two procedures to treat persistent atrial fibrillation
Part of Heart & circulation clinical trials.
This trial compares two minimally invasive heart procedures for persistent atrial fibrillation (a type of irregular heartbeat). The aim is to see which one is safer and more effective at restoring a normal heart rhythm.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You have been diagnosed with persistent atrial fibrillation.
- You have tried at least one heart rhythm medication (class I or III) without success or had side effects.
- You do not have severe heart valve problems that require surgery.
- You do not have a blood clot in your heart (left atrial thrombus).
- You do not have recent heart attack, very weak heart pump (LVEF 30% or less), or severe infection.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new type of heart procedure called pulsed field ablation for people with persistent atrial fibrillation (a long-lasting irregular heartbeat). It compares three different ways to use this ablation to try to restore a normal heart rhythm and reduce symptoms.
This trial tests two different catheters that use pulsed field energy to treat atrial fibrillation (a heart rhythm problem). It aims to find which one works better for people who need blood thinners but have a high risk of bleeding.
This study compares two procedures to treat persistent atrial fibrillation (an irregular heartbeat that lasts more than a week). It looks at whether a newer method (pulsed-field ablation) works better than the standard method (radiofrequency ablation), both combined with a chemical injection to improve treatment success.
This trial compares two different ways of delivering pulsed field ablation—a newer, targeted energy that zaps abnormal heart tissue—for people with atrial fibrillation. It aims to see if a single broader application works as well as a more focused, two-step approach, and it may help you feel better if you have symptoms from this irregular heartbeat.
This trial compares two ways to control atrial fibrillation (an irregular heartbeat) in older patients: destroying a small area of the heart's electrical pathway and implanting a pacemaker, versus a procedure to isolate the veins that trigger the irregular beats. The goal is to see which approach gives you better results and fits your preferences.
This study compares two types of ablation (a procedure that uses energy to fix irregular heartbeats) for people with persistent atrial fibrillation. It tests whether adding extra treatment to the back of the heart's left upper chamber helps improve outcomes compared to standard treatment alone.
Hear when a new Atrial Fibrillation (AF) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.