Comparing two ablation methods for persistent atrial fibrillation
Part of Heart & circulation clinical trials.
This trial tests a new type of ablation (pulsed field ablation) against standard radiofrequency ablation for people with persistent atrial fibrillation that hasn't been controlled well by medication. The goal is to see which method works better and is safer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You have been diagnosed with persistent atrial fibrillation (a type of irregular heartbeat that doesn't go away on its own).
- You have tried at least one heart rhythm medication (Class I or III) and it either didn't work or caused side effects.
- You do not have major heart valve problems that need surgery.
- You have no blood clot in your heart's upper left chamber (left atrial thrombus) on a recent scan.
- You have not had a recent heart attack and your heart's pumping strength is not severely weak (LVEF greater than 30%).
- You do not have a serious active infection.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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