Clin2
NCT06747728Possibly a fitRecruiting

Bevacizumab before surgery for new high-grade brain tumors

Brain Glioma

Treatments studied

Part of Brain & nervous system, Cancer clinical trials.

This trial tests whether giving bevacizumab (a drug that blocks blood vessel growth) before surgery helps treat newly diagnosed high-grade gliomas. It may be an option for adults who have not had prior anti-angiogenic therapy.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
20 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have a new, high-grade brain tumor (glioma) seen on scans.
  • Your daily functioning (KPS score) is at least 60 out of 100.
  • You have not been treated with drugs like Avastin (bevacizumab) before.
  • You do not have serious heart, lung, liver, or kidney disease.
  • You have not had a blood clot in the past 6 months.
  • You do not have active infections like tuberculosis or hepatitis.
  • Your blood pressure is well controlled, and you have no bleeding problems or unhealed wounds.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05518994Not yet recruiting· Phase 2
Immunotherapy plus low-dose bevacizumab for recurrent astrocytoma

This trial tests a combination of two drugs—sintilimab (an immunotherapy that helps your immune system fight cancer) and low-dose bevacizumab (a drug that blocks blood vessel growth to tumors)—for people with astrocytoma that has come back. The goal is to see if this combination can slow or stop the tumor's growth.

Zhengzhou, Henan
NCT05540275Not yet recruiting· Phase 2
Combination immunotherapy for recurrent glioblastoma after bevacizumab

This study tests a combination of two drugs for people with glioblastoma that has come back after treatment with bevacizumab (a drug that targets blood vessel growth). The goal is to see if this new combination can shrink the tumor or slow its growth.

Zhengzhou, Henan
NCT01269853Recruiting· Phase 1/Phase 2
Bevacizumab directly into brain arteries for recurrent brain tumors

This early-stage trial tests whether giving a targeted cancer medicine (bevacizumab) directly into brain arteries can help shrink or control certain recurrent (coming back) brain tumors. It may be an option if standard treatments are no longer working.

New York, New York
NCT05271240Recruiting· Phase 3
Targeted brain-artery drug added to standard treatment for new GBM

This Phase 3 trial tests whether delivering a cancer drug directly into brain blood vessels, along with standard radiation and temozolomide, works better than standard treatment alone in newly diagnosed glioblastoma (GBM). The goal is to improve control of the tumor while comparing side effects between the two approaches.

New York, New York
NCT06264531Recruiting· Phase 2/Phase 3
Bevacizumab for adults with symptomatic, untreatable brain AVMs

This trial tests a medication called bevacizumab (given as an IV infusion) to see if it can improve symptoms in people with brain arteriovenous malformations (AVMs) that cannot be treated with standard therapies. It is for those whose AVMs cause significant disability.

Paris, Île-de-France Region
NCT07439172Recruiting· Phase 2
Chemotherapy before radiation for newly diagnosed brain tumors

This trial tests giving a chemotherapy drug called temozolomide before radiation therapy to people with a newly diagnosed high-grade brain tumor. The goal is to see if this approach can help control the tumor better.

Camden, New Jersey

Hear when a new Brain Glioma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.