CD33 car-t cell therapy for returning or hard-to-treat aml
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests a personalized cell therapy called CD33 CAR-T for people whose acute myeloid leukemia has come back or isn't responding to standard treatments. The goal is to see if it's safe and can help eliminate leukemia cells that carry the CD33 protein.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- Your leukemia cells have a high level of the CD33 protein (over 80%) as shown on a lab test.
- Your cancer has returned after treatment or hasn't responded to at least two rounds of standard therapy.
- You have at least 5% leukemia cells in your bone marrow (by one test) or over 1% by another test.
- Your heart, liver, and kidney function are adequate, and you have no active lung infection or uncontrolled infections.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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