Minocycline for bleeding in the brain
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether an antibiotic called minocycline can help people who have had a bleeding stroke (intracerebral hemorrhage). The drug may reduce brain swelling and improve recovery. You must start treatment within 24 hours of the bleeding.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have a bleeding stroke in the brain (confirmed by a CT scan).
- You had no disability before the bleeding (could do daily activities on your own).
- You have moderate to severe weakness or other stroke symptoms (score of 6 or more on a stroke scale, with at least one limb significantly weak).
- You can start the study drug within 24 hours of the bleeding starting.
- You do not have other causes for the bleeding (like a tumor or aneurysm) and are not planning surgery for it.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This trial tests if the antibiotic minocycline can help people recover after a spontaneous brain bleed (intracerebral hemorrhage). It is for patients who have a moderate-sized bleed and are within 48 hours of symptoms starting.
This study tests whether the drug tranexamic acid can help stop bleeding in the brain when given early. It is for people with a spontaneous brain bleed who are awake and can be treated within 6 hours.
This study tests a combination of a minimally invasive surgery to remove the brain bleed and a medication called deferoxamine (which may help reduce damage from the bleed). The goal is to see if this combination helps improve recovery after a brain hemorrhage.
This trial tests a less invasive surgery to remove small blood clots (20–30 ml) in the basal ganglia, a deep part of the brain. It may help people who are awake but have a reduced level of consciousness after a recent brain bleed.
This trial tests if the antibiotic minocycline can help people recovering from a stroke. It is for adults who have had a stroke within the last 24 hours and have moderate symptoms based on a standard stroke scale.
This study tests whether an antibiotic called minocycline can reduce brain damage after doctors successfully remove a blood clot from the back of the brain (posterior circulation stroke) using a catheter procedure. The drug may help protect brain tissue and improve recovery.
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