Muscle and nerve changes after botox for stroke foot tightness
Part of Bones, joints & muscles, Brain & nervous system, Heart & circulation clinical trials.
This study looks at how botulinum toxin (botox) injections affect the muscles, tendons, and nerves in the lower leg of people who have had a stroke and have a tight, twisted foot (equinovarus). It aims to understand these changes to improve future treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had a stroke that affected only one side of your body.
- Your foot turns inward and downward due to muscle tightness after the stroke.
- You need a botox injection in your calf or leg muscles as part of your care.
- If you've had botox before in the same leg muscles, it must have been at least 3 months ago.
- You are not pregnant and are using effective birth control if you could become pregnant.
- You do not have other nerve or muscle problems (like Parkinson's or spinal cord injury) that affect your leg.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two treatments for leg stiffness after a stroke: dry needling (tiny needles placed in trigger points) and Botox injections. It may help you if you've had a first stroke within the past year and have mild to moderate tightness in the calf muscles that limits ankle movement.
This trial tests whether IPN10200, a Botox-like treatment, is safe and helps reduce stiff, tight upper-arm muscles caused by spasticity after stroke or brain injury. You may be able to join if you meet specific timing, prior-treatment, and muscle-stiffness measurements.
This trial compares two treatments—Botox injections or surgery—for arm and hand spasticity after a stroke, brain injury, or spinal cord injury. It may help you decide which option works best for you.
This study looks at whether combining Botox injections with other non-drug treatments (like physical therapy) is more effective for treating spasticity (muscle stiffness) than Botox alone. If you are already planning to get Botox for your spasticity, you may be able to participate.
This trial tests Xeomin (a type of botulinum toxin) to improve walking and leg mobility after stroke-related muscle stiffness. It’s for people who have spasticity (tight, stiff muscles) that affects how they clear their toes during walking.
This trial compares a freezing procedure (cryoneurotomy) with standard surgery to treat foot stiffness after a stroke. It aims to see which method better corrects the foot turning inward and downward, helping you walk more easily.
Hear when a new Stroke trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.