Cangrelor for heart attack patients on heart-lung support
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether adding a fast-acting anti-clotting drug (cangrelor) helps people having a massive heart attack who need a heart-lung machine (VA-ECMO). The goal is to see if it reduces clotting risks without causing dangerous bleeding.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had a massive heart attack with a shock or cardiac arrest that required a heart-lung machine (VA-ECMO).
- You need or have had a procedure to open blocked heart arteries (PCI).
- You have not taken any oral P2Y12 anti-clotting pills (like clopidogrel, prasugrel, or ticagrelor).
- You have not had a stroke or mini-stroke (TIA).
- You have no active, uncontrollable bleeding or suspected brain bleed.
- You are not pregnant and have no allergy to cangrelor.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study examines how blood clotting cells (platelets) behave when patients are on a heart-lung support machine called ECMO. Researchers will take small blood samples to understand if the machine affects platelet function and how to manage blood thinning medication safely.
This trial studies whether using a life-support machine called ECMO (extra support for the heart and lungs) helps people who develop shock right after a heart attack. It aims to improve outcomes when blood flow is failing and organs may be struggling.
This study looks at the best way to reopen blocked heart arteries (using a stent procedure) in people who had a heart attack complicated by severe shock and need a life-support machine called VA-ECMO. It may help improve outcomes by testing which revascularization approach works best for multi-vessel blockages.
This trial tests if cangrelor, a fast-acting blood thinner, can prevent small vessel damage during a planned stent placement in patients with stable chest pain. It may help improve blood flow to the heart muscle.
This trial tests whether a blood-thinner drug called cangrelor helps patients who are having a special type of bypass surgery that uses a small incision instead of opening the whole chest. The surgery connects a healthy artery from your chest wall directly to a blocked heart vessel to restore blood flow.
This study looks at how well a certain blood thinner (cangrelor) works when used as a 'bridge' before surgery or another procedure. It is for people who already need to be on this medicine for a short time.
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