New method to close PFO hole in heart
Part of Genetic & congenital, Heart & circulation clinical trials.
This trial is testing a new way to close a small hole in the heart (called a PFO) using a thin tube and a guidewire to make the procedure smoother. It's for people who have had a stroke or mini-stroke and whose PFO is thought to be the cause.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have been diagnosed with a patent foramen ovale (PFO) – a small hole in the heart that didn't close after birth. This must be confirmed by two types of heart ultrasound.
- You have had a stroke or a transient ischemic attack (TIA) that doctors couldn't explain (cryptogenic stroke or TIA).
- You are not pregnant.
- You do not have a blood clot in the heart, high blood pressure in the lungs (pulmonary hypertension), or heart valve disease.
- You have not had a heart attack, unstable angina, or a bleeding stroke in the past.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new device that sews shut a small hole in the heart (called a patent foramen ovale, or PFO). This hole may let tiny clots pass from the body to the brain, causing strokes or mini-strokes. If you have had a stroke or mini-stroke linked to this hole, this procedure might help prevent future events.
This trial tests a new device to close a PFO (a small hole between the upper chambers of the heart) in people who have had a stroke caused by a blood clot. The goal is to prevent future strokes by blocking the hole.
This trial looks at the safety and results of closing a PFO (a small hole in the heart) in people who have had a stroke or embolism with no other clear cause. If you qualify, doctors will close your PFO using a small tube inserted through a blood vessel and then follow your health over time.
This trial tests a new device to close a PFO (a small hole in the heart) in people who have had a stroke caused by a blood clot passing through that hole. The goal is to see if the device can prevent another stroke.
This study tests a new dissolvable device that closes a common heart defect called a patent foramen ovale (PFO), which can cause strokes. The device is designed to prevent future strokes and eventually break down in the body.
This trial tests whether closing a hole in the heart (a PFO) with a special device can help prevent another stroke after an unexplained stroke. You may be a candidate if your stroke likely happened because blood can pass through this PFO.
Hear when a new Patent Oval Foramen trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.