Biodegradable device to close the hole in the heart
Treatments studied
Part of Brain & nervous system, Genetic & congenital, Heart & circulation clinical trials.
This study tests a new dissolvable device that closes a common heart defect called a patent foramen ovale (PFO), which can cause strokes. The device is designed to prevent future strokes and eventually break down in the body.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have a patent foramen ovale (PFO), a small hole between the upper chambers of the heart.
- The hole allows a significant amount of blood to pass through, as shown by a bubble test.
- You have had a stroke or a mini-stroke (TIA) that your doctor believes was caused by the PFO.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at whether closing a small hole in the heart (called a PFO) can cause new heart rhythm problems. It is for people who had a stroke caused by a PFO and are planning to have it closed.
This trial tests whether a medicine called a beta-blocker can help prevent abnormal heart rhythms after a procedure to close a hole in the heart (PFO closure). If you are planning to have this closure, the medicine might reduce the risk of irregular heartbeats.
This trial studies ways to close a patent foramen ovale (PFO) to help prevent another stroke in people whose prior stroke had an unknown cause. If you qualify, you may receive one of the PFO closure approaches the study is comparing.
This trial tests a new device that sews shut a small hole in the heart (called a patent foramen ovale, or PFO). This hole may let tiny clots pass from the body to the brain, causing strokes or mini-strokes. If you have had a stroke or mini-stroke linked to this hole, this procedure might help prevent future events.
This trial tests a new device to close a PFO (a small hole between the upper chambers of the heart) in people who have had a stroke caused by a blood clot. The goal is to prevent future strokes by blocking the hole.
This trial tests a device called the Snowy PFO Closure System, which is meant to close a small hole in the heart (PFO) that can let blood clots pass to the brain and cause strokes or migraines. The device is inserted through a small tube, and the study aims to see if it is safe and works well.
Hear when a new Cardiovascular Diseases trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.