Clin2
NCT06795646Possibly a fitNot yet recruiting

Classifying fatty liver disease using liver biopsy

Metabolic Dysfunction Associated Steatotic Liver DiseaseMetabolic Dysfunction-associated Steatohepatitis (MASH)

Part of Digestive system, Hormones & metabolism clinical trials.

This study aims to better classify a common type of fatty liver disease (called MAFLD) using liver biopsy samples. It may help researchers understand different subtypes of the disease and could lead to more personalized care.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
2,000 people
Ages
Any age
Study type
Observational

Who can take part

  • You must have a fatty liver confirmed by ultrasound, plus at least one metabolic risk factor such as being overweight, high blood sugar, high triglycerides, low HDL cholesterol, or high blood pressure.
  • You must have already had a liver biopsy done (or be able to have one).
  • You must not drink a lot of alcohol (more than about 2 drinks a day for men or 1 drink a day for women).
  • You must not have hepatitis B or C.
  • You must not have a history of cancer, heart disease, chronic kidney disease, severe liver cirrhosis, or a liver transplant.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07082751Not yet recruiting
Predicting the course of fatty liver cirrhosis

This study aims to build a tool to predict how MASLD-related cirrhosis (fatty liver disease leading to liver scarring) will progress. It may help doctors and patients better understand the outlook and plan care.

Beijing, Beijing Municipality
NCT07188220Recruiting
Understanding patient views on fatty liver disease study

This study asks people with metabolic fatty liver disease and liver scarring about their experiences. It aims to learn what matters to you so doctors can improve care.

Barcelona
NCT07313007Recruiting
Gut bacteria chemicals in fatty liver disease

This study looks at whether the natural chemicals made by your gut bacteria from the food you eat could affect liver fat and health. If you have MASLD (a fatty liver condition), researchers want to measure these gut-produced substances to better understand the disease.

Pierre-Bénite
NCT06986447Enrolling by invitation
Non-invasive tests for serious liver disease

This study is testing whether advanced imaging and other non-invasive methods can properly identify people with significant liver scarring due to metabolic liver disease or alcohol-related liver disease. It may help find better ways to track liver health without repeated needle biopsies.

Chandler, Arizona
NCT06836609Recruiting· Phase 1/Phase 2
Study of a new drug for fatty liver disease (MASLD/MASH)

This study tests a new drug called ALN-CIDEB for people with fatty liver disease (MASLD or MASH). The goal is to see if it can reduce liver fat and improve liver health. You may qualify if you have a higher BMI and evidence of liver fat on imaging tests.

Chandler, Arizona
NCT07658755Recruiting
LiverSeek: Finding advanced liver scarring in MASLD

This study uses routine blood tests to find people with advanced liver scarring caused by a condition called MASLD. If you are between 50 and 75, have certain metabolic risks, and get blood work from your primary care doctor at select centers, you may be eligible.

Madrid, Madrid

Hear when a new Metabolic Dysfunction-Associated Steatotic Liver Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.