Intraoperative methadone for pain after head and neck cancer surgery
Part of Cancer, Ear, nose & throat, Lungs & breathing, Mouth & dental clinical trials.
This trial tests whether giving methadone during your head and neck cancer surgery helps control pain right after the operation. Methadone is a long-acting painkiller that might reduce pain for up to a day or more, potentially improving your recovery experience.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 89 years old.
- You have head or neck cancer (oral cavity, oropharynx, hypopharynx, or larynx).
- You are scheduled for surgery that involves removing cancer and may need flap reconstruction (moving tissue from another part of your body to rebuild the area).
- Your surgery is expected to last more than 4 hours (if you are having a pedicled flap).
- You are not currently using long-acting opioids (like OxyContin, MS Contin) for other pain conditions.
- You do not have severe kidney or liver problems, and your heart rhythm test (QT interval) is within normal limits.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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