Comparing two medicines for brain oxygen during surgery
Treatments studied
Part of Brain & nervous system, Pain clinical trials.
This study tests two different medicines, magnesium sulfate and dexmedetomidine, to see which one better maintains oxygen levels in the brain during surgery. This may help reduce the risk of brain-related complications after surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 21 and 60 years old.
- You are in good health overall (classified as ASA I or II by your anesthesiologist).
- You do not have a history of stroke, brain injury, or other brain conditions.
- You do not have serious heart or blood pressure problems, like uncontrolled high blood pressure or a recent heart attack.
- You are not currently taking certain heart or blood pressure medications (beta-blockers or calcium channel blockers).
- You are not on long-term opioid pain medication or magnesium supplements.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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