Clin2
NCT06858436Worth exploringNot yet recruiting

Canagliflozin during stroke clot removal

Acute Ischemic Stroke From Large Vessel Occlusion

Treatments studied

Part of Infections clinical trials.

This trial tests whether giving canagliflozin, a diabetes medication, during clot removal for stroke can improve recovery. It may help protect the brain after a stroke.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
150 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have had an acute ischemic stroke (a blocked blood vessel in the brain).
  • You are planning to have a procedure to remove the blood clot from your brain (mechanical thrombectomy).
  • You do not have severe kidney disease (stage 4 or 5) and are not on dialysis.
  • You have not taken an SGLT2 inhibitor medication (such as canagliflozin) in the last 3 months.
  • You are not allergic to canagliflozin.
  • You do not have type 1 diabetes and are not pregnant or breastfeeding.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06210633Recruiting
Clot removal trial for very large strokes

This trial tests a procedure called endovascular thrombectomy (clot removal through a catheter) for people with very large strokes. It aims to see if removing the clot can help even when a large part of the brain is already damaged.

Xiangtan, Hunan
NCT06715449Recruiting· Phase 2/Phase 3
Testing empagliflozin after a stroke with unknown cause

This trial tests if a diabetes drug called empagliflozin can help the heart's left atrium work better in people who have had a stroke with no known cause. You may join if you are getting a heart monitor device implanted to look for hidden irregular heartbeats.

Cambridge, Cambridgeshire
NCT06788626Not yet recruiting· Phase 3
Testing a medication after clot removal for major stroke

This study tests whether a medication called a GLP-1 receptor agonist (a type of drug used for diabetes) can improve recovery after a major stroke that was treated with a procedure to remove the blood clot. The goal is to see if this drug helps reduce further brain damage and improve outcomes.

Hefei, Anhui
NCT07105917Not yet recruiting· Phase 3
SGLT2 inhibitor for brain protection after acute stroke

This trial tests whether a medicine called an SGLT2 inhibitor, which is usually used for diabetes, can help protect the brain and improve recovery when given soon after a stroke. It is for people who had a stroke within the last 3 days and have moderate to severe symptoms.

NCT07511543Not yet recruiting· Phase 2
Studying a diabetes drug to improve recovery after stroke surgery

This trial tests whether a medication commonly used for diabetes can help patients who had a stroke due to a blocked large artery in the brain. The drug is given as an injection after the standard procedure to remove the blood clot, and researchers will see if it leads to better recovery.

NCT07527390Not yet recruiting· Phase 4
Canagliflozin in dialysis patients

This study tests whether the drug canagliflozin (a type of diabetes medicine) is safe and works in people on dialysis. It may help improve fluid balance or blood sugar control in hemodialysis patients.

Groningen, Provincie Groningen

Hear when a new Acute Ischemic Stroke From Large Vessel Occlusion trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.