Clin2
NCT07105917Possibly a fitNot yet recruiting

SGLT2 inhibitor for brain protection after acute stroke

Acute Ischemic Stroke

Treatments studied

Part of Brain & nervous system, Heart & circulation clinical trials.

This trial tests whether a medicine called an SGLT2 inhibitor, which is usually used for diabetes, can help protect the brain and improve recovery when given soon after a stroke. It is for people who had a stroke within the last 3 days and have moderate to severe symptoms.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
1,050 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You had a stroke within the last 3 days.
  • Your stroke symptoms are moderate to severe (measured by a standard scale).
  • You were able to do your usual daily activities before the stroke (no major disability).
  • You do not have type 1 diabetes, heart failure, or severe kidney or liver problems.
  • You have not taken an SGLT2 inhibitor in the past 4 weeks.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06788626Not yet recruiting· Phase 3
Testing a medication after clot removal for major stroke

This study tests whether a medication called a GLP-1 receptor agonist (a type of drug used for diabetes) can improve recovery after a major stroke that was treated with a procedure to remove the blood clot. The goal is to see if this drug helps reduce further brain damage and improve outcomes.

Hefei, Anhui
NCT06137300Not yet recruiting
Study of a new drug for acute stroke from narrowed brain arteries

This trial tests whether a drug called urinary kallidinogenase can help people who have had a stroke caused by a blocked artery in the brain. The drug is given within 48 hours of the stroke, and the study hopes to see if it improves recovery and reduces disability.

Changchun, Jilin
NCT06085378Not yet recruiting
Study of a drug for stroke with diabetes

This trial tests a drug called urinary kallidinogenase in people who have had a stroke and also have type 2 diabetes. The drug may help improve recovery after a stroke.

Guangzhou, Guangdong
NCT04899479Recruiting· Phase 4
SGLT-2 inhibitor after heart attack to improve heart recovery

This trial studies whether starting an SGLT-2 inhibitor around the time of a heart attack can reduce heart damage size and improve how the heart heals. It focuses on people with a high risk of developing heart failure and who are getting a procedure to open blocked heart arteries.

Seoul
NCT05305911Recruiting· Phase 2
SGLT2 drug after first heart attack to reduce heart damage

This Phase 2 trial tests whether an SGLT2 medicine started after a first STEMI heart attack can reduce ongoing heart muscle injury and scarring. It may help people who, based on heart imaging, have larger infarcts and ongoing microvascular damage.

Minneapolis, Minnesota
NCT06009874Recruiting
SGLT2 inhibitor early after heart attack to protect the heart

This study tests whether giving an SGLT2 inhibitor (a diabetes medicine that may also protect the heart) early after a heart attack can help shield the heart from damage. It is for people having a first-time STEMI heart attack who have adequate kidney function and stable blood pressure.

Shibīn al Kawm, Menofia

Hear when a new Acute Ischemic Stroke trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.